What is 2-wheeled luggage? These are suitcases with only two wheels. The tilt back on their wheels to be able to roll. A two-wheeled suitcase gives you a little more packing room inside the bag. Two wheeled carry-ons fit more snugly into the sizer bins at the airport. If you prefer the classic 2 wheels over the more trendy 4 wheels, search below for some options.